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According to the researchers, retatrutide-treated diabetic rats showed partial preservation of hippocampal and cortical tissue organization compared with untreated diabetic animals

In a murine diet-induced obesity (DIO) model, after 25 days of treatment, results demonstrated: Greater than 30% weight loss when nimacimab was combined with the dual GLP-1/GIP agonist, tirzepatide Nimacimab alone demonstrated 23.5% weight loss, comparable to monlunabant and tirzepatide alone

The safety profile compares favorably to alternatives such as NSAIDs and corticosteroids, which carry major risks with long-term use